As the fusion reactors can be turned off as soon as you land and only turned on again during take off you can save on radiation shielding and only put the radiation shadow shielding on the side facing the passengers you can also moke use of distance reducing the thickness of shielding required, by putting the all the reactors together in two pods underneath the two wings as far away from the passenger compartment as the wings structure can take it. 8 focus units per pod for redundancy if you want a unit in the body of the plane for emergency power in the tail behind a shadow shield but the two pods should be enough. Where the central fuel tank usually is is now more cargo space. The wing fuel tanks now recirculated coolant. This might not make flight as cheap as you might think see
But the airframe could be made heavier and more rugged for more pressurization cycles. Unlimited range with no refueling stops on smaller planes.
As the lifetime of the pressurised cabin will be the main cost. Low flying slower aircraft will become a cheap method of travel. Megawatt quadcopters will be sky busses flying between helipads anywhere as cheap as any commuter train or bus.