Interesting idea…
From previous work I gather the optimum ratio for the p+B11 is nearer 5 parts hydrogen to one part Boron to keep the average Z value down, and so lessen the bremstralung losses.
If you had a mix of deuterium gas with natural decaborane (which has chemical formula B10H14) with the boron in it having the natural 20:80 ratio of B-10 to B-11. Then you don’t have to worry about separating out the boron isotopes. The B-10 in the system can react both with the deuterium (I’ve no idea what the cross-section for this is), but also mop up some of the unwanted neutrons from the D-D reactions in the reaction n + B-10 -> Li-7 + He-4
The overall number of neutrons escaping would still be larger than pure p+B11 but if it gets over the hurdle to achieve ignition then it may be worth it.