As i said before, it can be minimized to the point of being manageable. If we are talking 100s of DT shots for a year and total T inventory needs to be large (aka 1g or so) then its a licencing nightmare, and activation is a serious problem (assuming you get burns). But if its much smaller and you don’t need to do so many shots, it really shouldn’t be a problem, at least not a big one. The radioactivity from a single shot would decay quickly (hours or so) But do tend to be gammas. Again its manageable.
If what you wanted to do was show breakeven or even burn with DT, then such a program does not need 100s of shots. And if done…. well i don’t think your going to have problems with grants again. At least for a while.