Hi meems,
There are practical problems that arise with higher pressures. Shock waves can damage equipment as LPPFusion found out in these early experiments: https://lppfusion.com/breaking-records-and-window/.
I haven’t looked up the link yet but I remember reading an article that the plan is to increase pressures to reduce the percentage of impurities from the electrodes. This will also increase the fusion yields. That requires higher currents to maintain high temperatures in the larger mass of fuel. The power delivery system will be reconfigured to provide those higher currents.
I don’t know if plasmoids can form in starting conditions using liquids or solids. I suppose it is possible to engineer a system that could do that. A dpf is a type of particle accelerator that concentrates the beam into a tiny volume and compresses it with a strong magnetic field.
It is possible to pass a very large current through a liquid or a solid, convert that to a plasma and compress it with a strong current and magnetic field.
That would be close to what a Z machine does if it had a liquid or solid target. http://www.sandia.gov/z-machine/about_z/how-z-works.html It does not have the particle accelerator function that a dpf has and relies on heating and compression from a very large current.